阿片类物质中毒

定义

阿片类药物中毒是在服用阿片类药物期间或之后不久出现的一种具有临床意义的暂时性情况，其特征是意识、认知、感知、情感、行为或协调障碍。这些障碍是由阿片类药物的已知药理作用引起，其强度与阿片类药物的用量密切相关。有时间限制，随阿片类物质从体内清除而减弱。表现特征可能包括嗜睡、木僵、情绪变化（如欣快，随后出现淡漠和躁动）、精神运动迟缓、判断力受损、呼吸抑制、口齿不清、记忆力和注意力受损。严重中毒可能会导致昏迷。典型体征是瞳孔收缩，但如果是合成阿片类药物中毒时，则可能没有这一体征。重度阿片类药物中毒可导致呼吸抑制死亡。

Opioid intoxication is a clinically significant transient condition that develops during or shortly after the consumption of opioids that is characterised by disturbances in consciousness, cognition, perception, affect, behaviour, or coordination. These disturbances are caused by the known pharmacological effects of opioids and their intensity is closely related to the amount of opioids consumed. They are time-limited and abate as opioids are cleared from the body. Presenting features may include somnolence, stupor, mood changes (e.g. euphoria followed by apathy and dysphoria), psychomotor retardation, impaired judgment, respiratory depression, slurred speech, and impairment of memory and attention. In severe intoxication coma may ensue. A characteristic physical sign is pupillary constriction but this sign may be absent when intoxication is due to synthetic opioids. Severe opioid intoxication can lead to death due to respiratory depression.

除外词 明确排除、需编到其他条目的情况

• 附体出神障碍6B63
• 芬太尼中毒NE60
• 羟考酮中毒NE60
• 阿片类中毒NE60

索引词 可用于检索该条目的同义词与别名

• 阿片类物质中毒
• 海洛因中毒
• 阿片类物质所致恶性体验
• 急性芬太尼中毒
• 芬太尼和去丙酰芬太尼中毒
• 芬太尼和乙酰芬太尼中毒
• 急性芬太尼和海洛因复合效应中毒
• 急性芬太尼和海洛因中毒
• 芬太尼和海洛因中毒
• 吗啡中毒
• 吗啡毒性
• 急性美沙酮中毒
• 美沙酮中毒
• 羟考酮中毒