4A41.2
包涵体肌病
Inclusion body myopathy
- 上级条目
- 4A41 特发性炎性肌病
- 层级
- 4 级
定义
包涵体肌病（IBM）与多发性肌炎（PM）和皮肌炎（DM）在临床和组织病理学上有明显区别。特征性临床表现是在数月到数年内隐匿性肌无力发作，主要局限于大腿肌肉和手指屈肌的肌无力，以及对糖皮质激素治疗的抵抗。典型的组织病理学特征包括肌浆、核内含物和边缘空泡。
Inclusion body myopathy (IBM) is distinguished from polymyositis (PM) and dermatomyositis (DM) on the basis of clinical and histopathological features. A characteristic clinical phenotype is characterised by insidious onset of muscle weakness over months to years, muscle weakness localised predominantly in the thigh muscles and finger flexors, and resistance to glucocorticoid treatment. Typical histopathologic features include sarcoplasmic and nuclear inclusions and rimmed vacuoles.
子条目 共 3 条
后组配轴 Postcoordination
该条目未定义后组配轴，直接使用上面的编码即可。后组配是在主干编码之后追加侧别、具体解剖部位、严重程度、病因等细节的可选组合方式，不是必填项。