糙皮病所致痴呆

定义

糙皮病所致痴呆是由于饮食中持续缺乏维生素 B3（烟酸）或色氨酸，或由于疾病（如克罗恩病）或某些药物（如异烟肼）的影响导致胃肠道吸收不良。糙皮病的核心症状包括皮肤病（对阳光敏感、皮损、脱发和水肿）和腹泻。如果长期营养缺乏，出现认知症状，包括攻击性、运动障碍（共济失调和烦躁不安）、意识模糊和虚弱。补充营养（如烟酸）治疗通常可使症状逆转。

Dementia due to pellagra is caused by persistent lack of vitamin B3 (niacin) or tryptophan either in the diet or due to poor absorption in the gastrointestinal tract due to disease (e.g., Crohn disease) or due to the effects of some medications (e.g., isoniazid). Core signs of pellagra include dermatological changes (sensitivity to sunlight, lesions, alopecia, and oedema) and diarrhoea. With prolonged nutritional deficiency cognitive symptoms that include aggressivity, motor disturbances (ataxia and restlessness), confusion, and weakness are observed. Treatment with nutritional supplementation (e.g., niacin) typically results in reversal of symptoms.

索引词 可用于检索该条目的同义词与别名

• 糙皮病所致痴呆
• 烟酸缺乏症所致痴呆