5C64.10
铁过多疾病
Iron overload diseases
- 上级条目
- 5C64.1 铁代谢紊乱
- 层级
- 6 级
定义
铁超载是指过量的铁在身体组织中积聚。铁过载通常是由于吸收和储存过量铁的遗传倾向而发生的，最常见的形式是遗传性血色病。铁过载也可作为其他血液病的并发症发生，需要长期输血治疗，反复注射肠外铁，或过量摄入铁。过量铁储存通常积聚在网状内皮组织中，并造成少量损害（"含铁血黄素沉着症"）。如果超负荷持续下去，铁最终开始积聚在肝实质、胰腺、心脏和滑膜等组织中，引起血色病。
Iron overload is the accumulation of excess iron in body tissues. Iron overload usually occurs as a result of a genetic predisposition to absorb and store iron in excess amounts, the most common form of which is hereditary hemochromatosis. Iron overload can also occur as a complication of other hematologic disorders that require chronic transfusion therapy, repeated injections of parenteral iron, or excessive iron ingestion. Excessive iron stores usually accumulate in the reticuloendothelial tissues and cause little damage (“hemosiderosis”). If overload continues, iron eventually begins to accumulate in tissues such as hepatic parenchyma, pancreas, heart and synovium, causing hemochromatosis.
跨章引用 同一概念在其他章节另有编码
索引词 可用于检索该条目的同义词与别名
- 铁过多疾病
- 特发性含铁血黄素沉着症
- 含铁血黄素沉着症
- 遗传性血色病
- HFE-相关的遗传性血色病，1型
- C282Y / C282Y血色病
- 经典的血色病
- 血色素沉着症引起的关节病
- 少年遗传性血色病，2型
- 少年遗传性血色病，2A型
- 血幼素相关的血色病
- 少年遗传性血色病，2B型
- 铁调素相关血色病
- 非HFE相关的遗传性血色病，3型
- TFR2相关的血色病
- 非HFE相关的遗传性血色病，4型
- 常染色体显性遗传性血色病
- 膜铁转运蛋白缺陷引起的血色素沉着症
- 膜铁转运蛋白病
- 继发性铁超负荷
- 非洲铁超负荷
- 撒哈拉以南非洲铁超负荷
- 班图血红素
- 饮食性含铁血黄素沉着病
- 脑组织铁沉积神经变性病
- NBIA[脑组织铁沉积神经变性病]
- 苍白球色素性萎缩
- 色素；变性，苍白球（进行性）
- 苍白球色素性变性
- 哈-斯二氏病（弃用）
- 线粒体膜蛋白相关神经变性病
- C19orf12基因突变所致脑铁沉积性神经变性病
- MPAN - [线粒体膜蛋白相关神经变性]
- NBIA4 - [脑铁沉积性神经变性病4型（NBIA4）]
- 脑铁沉积性神经变性病4型
- 线粒体膜蛋白相关神经退行性病变
- 泛酸激酶相关性神经变性病
- NBIA1[脑组织铁沉积神经变性病1型]
- PKAN[泛酸激酶相关神经变性]
- PANK2 基因突变相关神经退行性疾病
- HARP[低脂蛋白血症,棘红细胞增多症,视网膜色素变性,和苍白球变性]
- HSS[Hallervorden-Spatz综合征]（弃用）
- 脑组织铁沉积神经变性病1型
- 泛酸激酶相关的神经退行性变
- 泛酸激酶相关神经退行性疾病
- 非典型泛酸激酶相关的神经变性病
- NBIA1[脑组织铁沉积神经变性病1型]，非典型
- PKAN[泛酸激酶相关神经变性]，非典型
- 神经变性与脑铁积累1型，非典型
- 经典型泛酸激酶相关的神经变性病
- NBIA1[脑组织铁沉积神经变性病1型]，经典型
- PKAN[泛酸激酶相关神经退行性变]，经典型
- 脑组织铁沉积神经变性病1型，经典型
- β-螺旋蛋白相关性神经变性病
- BPAN[β-螺旋蛋白相关性神经变性病]
- NBIA5[神经变性病伴脑铁沉积症5型]
- 神经变性病伴脑铁沉积症5型
- 神经退行性变伴脑铁沉积症5型
- 脑组织铁沉积神经变性病5型
- 辅酶A合成酶相关性神经变性病
- CoPAN[辅酶A合成酶相关性神经变性病]
- PLA2G6相关神经退行性疾病
- NBIA 2 PLA2G6突变
- PLAN - [PLA2G6相关神经退行性疾病]
- PARK14 - [帕金森病14号基因]
- 脑铁沉积性神经退行性疾病2型
- NBIA2 - [脑铁沉积性神经退行性疾病2型]
- 婴儿神经轴索萎缩
- INAD[婴儿神经轴索萎缩]
- Seitelberger病（已弃用）
- 塞氏病
- 婴儿神经轴索营养不良
- 塞提耳伯格病
- 赛特贝格病
- Kufor-Rakeb综合征
- KRS[Kufor-Rakeb综合征]
- PARK9[帕金森病9型]
- 帕金森病9型
- 常染色体隐性遗传性痉挛性截瘫35型
- 脂肪酸羟化酶相关性神经变性
- FAHN - [脂肪酸羟化酶相关性神经变性]
- 痉挛性截瘫35型
- SPG35 - [痉挛性截瘫35型]
- 获得性血色素沉着症
- 获得性铁超负荷
- 新生儿血色病
英文词条（77）
- Iron overload diseases
- hemosiderosis
- idiopathic haemosiderosis
- Hereditary haemochromatosis
- HFE-related hereditary haemochromatosis, Type 1
- C282Y/C282Y haemochromatosis
- Classic haemochromatosis
- Arthropathy in haemochromatosis
- Juvenile hereditary haemochromatosis, Type 2
- Juvenile hereditary haemochromatosis, Type 2A
- Hemojuvelin-related haemochromatosis
- Juvenile hereditary haemochromatosis, Type 2B
- Hepcidin-related haemochromatosis
- Non-HFE-related hereditary haemochromatosis, Type 3
- TFR2-related haemochromatosis
- Non-HFE-related hereditary haemochromatosis, Type 4
- Autosomal dominant hereditary haemochromatosis
- Ferroportin disease
- Haemochromatosis due to defect in ferroportin
- Secondary iron overload
- African iron overload
- Bantu haemosiderosis
- Iron overload in sub-Saharan Africa
- Dietary haemosiderosis
- Neurodegeneration with brain iron accumulation
- Hallervorden-Spatz disease (deprecated)
- NBIA - [Neurodegeneration with brain iron accumulation]
- pigmentary pallidal atrophy
- pigmentary pallidal degeneration
- progressive pigmentary pallidal degeneration
- Mitochondrial Membrane Protein-Associated Neurodegeneration
- MPAN - [Mitochondrial Membrane Protein-Associated Neurodegeneration]
- NBIA4 - [Neurodegeneration with Brain Iron Accumulation type 4]
- Neurodegeneration with Brain Iron Accumulation type 4
- Neurodegeneration with brain iron accumulation due to C19orf12 mutation
- Pantothenate-kinase-associated neurodegeneration
- HARP - [hypoprebetalipoproteinemia, acanthocytosis, retinitis pigmentosa, and pallidal degeneration]
- HSS - [Hallervorden-Spatz-Syndrome] (deprecated)
- NBIA1 - [Neurodegeneration with brain iron accumulation type 1]
- Neurodegeneration with brain iron accumulation type 1
- PANK2 gene mutation-associated neurodegeneration
- PKAN - [Pantothenate-kinase-associated neurodegeneration]
- Atypical pantothenate kinase associated neurodegeneration
- NBIA1 - [Neurodegeneration with brain iron accumulation type 1] atypical form
- Neurodegeneration with brain iron accumulation type 1, atypical form
- PKAN - [Pantothenate-kinase-associated neurodegeneration] atypical form
- Classic pantothenate kinase associated neurodegeneration
- NBIA1 - [Neurodegeneration with brain iron accumulation type 1] classic form
- Neurodegeneration with brain iron accumulation type 1, classic form
- PKAN - [Pantothenate-kinase-associated neurodegeneration] classic form
- Beta-Propeller protein-associated neurodegeneration
- BPAN - [Beta-Propeller protein-associated neurodegeneration]
- NBIA5 - [Neurodegeneration with brain iron accumulation type 5]
- neurodegeneration with brain iron accumulation type 5
- COASY Protein-Associated Neurodegeneration
- CoPAN - [COASY Protein-Associated Neurodegeneration]
- PLA2G6-associated neurodegeneration
- NBIA 2 PLA2G6 mutation
- NBIA2 - [Neurodegeneration with brain iron accumulation type 2]
- Neurodegeneration with brain iron accumulation type 2
- PARK14 - [Parkinson disease 14]
- PLAN - [PLA2G6-Associated Neurodegeneration]
- Infantile neuroaxonal dystrophy
- INAD - [Infantile neuroaxonal dystrophy]
- Seitelberger disease (deprecated)
- Kufor-Rakeb syndrome
- KRS - [Kufor-Rakeb syndrome]
- PARK9 - [Parkinson Disease Type 9]
- Parkinson Disease Type 9
- Autosomal recessive spastic paraplegia type 35
- FAHN - [Fatty Acid Hydroxylase-Associated Neurodegeneration]
- Fatty Acid Hydroxylase-Associated Neurodegeneration
- SPG35 - [Spastic Paraplegia 35]
- Spastic Paraplegia 35
- Acquired hemochromatosis
- Acquired iron overload
- Neonatal haemochromatosis
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