2型发作性睡病

定义

2 型发作性睡病是一种过度嗜睡的疾病，其特征是每天都有无法抑制的睡眠需求或白天进入睡眠状态，在下视丘分泌素（食欲素）信号正常的情况下，多次睡眠潜伏期试验（MSLT/PSG）结果显示快速眼动睡眠表现异常。也就是说，脑脊液（CSF）下视丘分泌素测定值>110 皮克/毫升。不存在猝倒。这种疾病不是由神经系统疾病或其他疾病引起。 注：明确诊断需要每天都有无法抑制的睡眠需求或白天进入睡眠状态，以及嗜睡症特有的多次小睡睡眠潜伏期试验/多导睡眠监测（MSLT/PSG）结果。应该无猝倒或脑脊液下视丘分泌素缺乏的证据（如检查了）。

Type 2 narcolepsy is a disorder of excessive sleepiness characterised by daily periods of irrepressible need to sleep or daytime lapses into sleep and abnormal manifestations of REM sleep as demonstrated by multiple sleep latency test (MSLT/PSG) findings in the context of normal hypothalamic hypocretin (orexin) signaling. That is, cerebrospinal fluid (CSF) hypocretin determinations are > 110 picograms per milliliter. Cataplexy is not present. The disorder is not attributable to another disease of the nervous system or other medical condition. Note: A definitive diagnosis requires daily periods of irrepressible need to sleep or daytime lapses into sleep and multiple sleep latency test/polysomnography (MSLT/PSG) findings characteristic of narcolepsy. There should be no evidence of cataplexy or CSF hypocretin deficiency (if testing is performed).

索引词 可用于检索该条目的同义词与别名

• 2型发作性睡病
• 不伴猝倒和下丘脑分泌素缺乏的发作性睡病