Stevens-Johnson综合征或中毒性表皮坏死松解症
Stevens-Johnson syndrome or toxic epidermal necrolysis
- 层级
- 4 级
定义
影响皮肤和粘膜的一系列严重和危及生命的超敏反应性疾病，最常见的是对药物的特异性反应。Stevens-Johnson综合征（SJS）总是累及粘膜表面，但根据定义，皮肤受累仅限于<10%的体表面积（BSA）。中毒性表皮坏死松解症（TEN）有时可能不涉及粘膜，但根据定义，皮肤受累的BSA含量大于30%。一种中间形式是粘膜受累伴10-30%BSA的皮肤受累（SJS-TEN重叠综合征）。所有形式都会导致广泛脱屑和溃疡，并具有致命的重大风险。
A spectrum of severe and life-threatening hypersensitivity disorders affecting skin and mucous membranes, most commonly precipitated by an idiosyncratic reaction to medication. Stevens-Johnson syndrome (SJS) always involves mucosal surfaces but the skin involvement is limited by definition to <10% body surface area (BSA). Toxic epidermal necrolysis (TEN) may sometimes spare mucous membranes but skin involvement is by definition >30% BSA. An intermediate form is recognised in which mucosal involvement is accompanied by skin involvement of 10-30% BSA (SJS-TEN overlap syndrome). All forms result in extensive sloughing and ulceration and carry a significant risk of fatal outcome.
跨章引用 同一概念在其他章节另有编码
索引词 可用于检索该条目的同义词与别名
- Stevens-Johnson综合征或中毒性表皮坏死松解症
- SJS/TEN [Stevens-Johnson综合征和中毒性表皮坏死松解症]
- 重症多形红斑或中毒性表皮坏死松解症
- SJS/TEN [史蒂文斯-约翰逊综合征和中毒性表皮坏死松解症]
英文词条（2）
- Stevens-Johnson syndrome or toxic epidermal necrolysis
- SJS/TEN - [Stevens-Johnson syndrome and toxic epidermal necrolysis]
子条目 共 3 条
后组配轴 Postcoordination
该条目未定义后组配轴，直接使用上面的编码即可。后组配是在主干编码之后追加侧别、具体解剖部位、严重程度、病因等细节的可选组合方式，不是必填项。