中毒性表皮坏死松解症
Toxic epidermal necrolysis
- 层级
- 5 级
定义
中毒性表皮坏死松解症（TEN）是一种危及生命的急性皮肤病，通常引用的总死亡率风险在25%到30%之间，但在受影响最严重的患者中，死亡的风险约为90%（SCORTEN评分>5）。其特征是迅速出现广泛红斑、坏死和大疱性表皮脱落（>30%的体表面积）。通常，粘膜也会受累。脓毒症、体液耗竭和多器官衰竭可能导致死亡。在三分之二的病例中，TEN是由可明确识别的药物过敏引发。
Toxic epidermal necrolysis (TEN) is an acute life-threatening skin disease with commonly quoted overall risk of mortality of between 25 and 30%, though the risk of fatal outcome is around 90% in the most severely affected patients (SCORTEN score >5). It is characterised by the rapid onset of extensive erythema, necrosis, and bullous detachment of the epidermis (> 30% body surface area). Commonly, the mucous membranes are also involved. Death may result from a combination of sepsis, fluid depletion and multi-organ failure. In two thirds of cases, TEN is triggered by a clearly identifiable drug allergy.
跨章引用 同一概念在其他章节另有编码
索引词 可用于检索该条目的同义词与别名
- 中毒性表皮坏死松解症
- Lyell综合征
- TEN[中毒性表皮坏死松解症]
- Lyell综合征[中毒性表皮坏死松解症]
英文词条（4）
- Toxic epidermal necrolysis
- Lyell syndrome
- Lyell syndrome (toxic epidermal necrolysis)
- TEN - [toxic epidermal necrolysis]
后组配轴 Postcoordination
该条目未定义后组配轴，直接使用上面的编码即可。后组配是在主干编码之后追加侧别、具体解剖部位、严重程度、病因等细节的可选组合方式，不是必填项。