4A43.2
干燥综合征
Sjögren syndrome
- 层级
- 4 级
定义
干燥综合征是一种缓慢进展的全身性炎症性自身免疫疾病，主要影响外分泌腺体。淋巴细胞浸润取代功能性上皮，导致口腔和眼部干燥。产生特征性的自身抗体（如抗-Ro/SS-A和/或抗-La/SS-B）。这种疾病可以单独发生（称为 "原发性SS"）或与另一种自身免疫性疾病有关（称为 "继发性SS"）。
Sjögren syndrome (SS) is a slowly progressive, systemic inflammatory autoimmune disease affecting primarily the exocrine glands. Lymphocytic infiltrates replace functional epithelium, leading to oral and ocular dryness. Characteristic autoantibodies (e.g., anti-Ro/SS-A and/or anti-La/SS-B) are produced. The disorder can occur alone (it is then known as “primary SS”) or in association with another autoimmune disease (it is then known as “secondary SS”).
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子条目 共 5 条
后组配轴 Postcoordination
后组配是在主干编码之后追加的可选扩展轴（如侧别、具体解剖部位、严重程度），用于把「部位 + 侧别 + 病程」等细节一次表达完整。只有标注「必填」的轴在组合编码时必须给出，其余可留空。
- 临床表现hasManifestation可选