Lambert-Eaton综合征
Lambert-Eaton syndrome
- 层级
- 4 级
定义
Lambert-Eaton肌无力综合征是乙酰胆碱受体阳性重症肌无力的20倍，患病率为3.42‰，是一种免疫介导的神经肌肉连接疾病。临床上该病特点是腿部近端无力。大多数病人的无力延伸到其他肌肉，包括眼睑肌肉。自主神经症状（口干，勃起功能障碍，便秘）是常见的。肌腱反射减弱。重复性神经刺激显示低的复合肌肉动作电位，在低频率下递减>10%，在高频率下最大自主收缩后递增>100%。
Lambert-Eaton myasthenic syndrome, 20 times as rare as acetylcholine receptor positive myasthenia gravis with a prevalence of 3.42 per million, is an immune-mediated disease of the neuromuscular junction. Clinically the disease is characterised by proximal weakness of the legs. In most patients, the weakness extends to other muscles including the oculobulbar ones. Autonomic symptoms (dry mouth, erectile dysfunction, constipation) are frequent. Tendon reflexes are reduced. Repetitive nerve stimulation shows low compound muscle action potentials, decrement > 10% at low frequency and increment > 100% after maximum voluntary contraction at high frequency.
索引词 可用于检索该条目的同义词与别名
- Lambert-Eaton综合征
- LEMS[Lambert-Eaton肌无力综合征]
- Lambert-Eaton肌无力综合征
- Eaton-Lambert综合征
- 兰伯特-伊顿综合征
- 副肿瘤性Lambert-Eaton综合征
- 与恶性肿瘤相关的Lambert-Eaton综合征
- 副肿瘤性Lambert-Eaton肌无力综合征
- 与恶性肿瘤相关的兰伯特-伊顿综合征
- 副肿瘤性兰伯特-伊顿综合征
- 副肿瘤性兰伯特-伊顿肌无力综合征
- 与电压门控钙通道相关的Lambert-Eaton肌无力综合征
- Lambert-Eaton肌无力-肌病综合征
- 与电压门控钙通道相关的兰伯特-伊顿肌无力综合征
- 兰伯特-伊顿肌无力-肌病综合征
- 与SOX相关的Lambert-Eaton肌无力综合征
- 自身免疫性获得性Lambert-Eaton综合征
- 抗体阳性Lambert-Eaton综合征
- 抗体阳性Lambert-Eaton肌无力综合征
- 抗体阳性兰伯特-伊顿肌无力综合征
- 抗体阳性兰伯特-伊顿综合征
- 自身免疫性获得性兰伯特-伊顿综合征
英文词条（13）
- Lambert-Eaton syndrome
- Eaton-Lambert syndrome
- LEMS - [Lambert-Eaton myasthenic syndrome]
- Lambert-Eaton myasthenic syndrome
- Paraneoplastic Lambert Eaton syndrome
- Lambert-Eaton syndrome, malignancy association
- Paraneoplastic Lambert Eaton myasthenic syndrome
- Voltage-gated calcium channel-associated Lambert-Eaton myasthenic syndrome
- Myasthenic-Myopathic syndrome of Lambert-Eaton
- SOX-associated Lambert-Eaton myasthenic syndrome
- Lambert-Eaton syndrome, autoimmune-acquired
- Lambert-Eaton myasthenic syndrome, antibody positive
- Lambert-Eaton syndrome, antibody positive
后组配轴 Postcoordination
该条目未定义后组配轴，直接使用上面的编码即可。后组配是在主干编码之后追加侧别、具体解剖部位、严重程度、病因等细节的可选组合方式，不是必填项。