并肢畸形

定义

人体鱼序列征是一种罕见的致死性畸形，其特征是胎儿尾部严重畸形，包括单一下肢，包括同一皮肤干轴的单一股骨到分开独立股骨的不同程度受累，存在双足（双足并腿畸形）或单足（单足并腿畸形），无双足（无足并腿畸形）。泌尿生殖道异常也存在，包括双侧先天性肾缺如、无流出道和无外生殖器。肛门闭锁和腰骶尾椎缺失也有报道。这些畸形共同构成了尾端退化综合征的极端形式。

Sirenomelia is a rare lethal malformation characterised by severe anomalies of the caudal part of the fetus that include a single lower limb, with various degrees of involvement ranging from single to separate femurs in the same skin shaft, presence of two feet (sympode mermaid) or one foot (monopode mermaid), to absence of both feet (ectromelic mermaid). Urogenital anomalies are also present and include bilateral renal agenesis, absence of outflow tract and absence of external genitalia. Imperforate anus and sacro-coccygeal agenesis have also been reported. Together these malformations comprise the extreme form of the caudal regression sequence.

索引词 可用于检索该条目的同义词与别名

• 并肢畸形
• 人体鱼序列综合征
• 并腿畸形
• 人体鱼序列征