特发性中枢性肺泡低通气

定义

特发性中枢性肺泡低通气的定义是，肺泡通气减少导致睡眠相关的高碳酸血症和低氧血症，而患者的肺和呼吸泵机械特性假定正常。睡眠期间存在慢性低通气，但没有任何易于识别的呼吸障碍，如肺部气道或实质病症、神经、神经肌肉或胸壁异常、严重肥胖、其他与睡眠相关的呼吸障碍或使用呼吸抑制药物或物质。日间和夜间通气不足被认为主要是由于对二氧化碳（CO2）和氧气（O2）的化学感受性减弱所致。患者可能主诉晨起头痛、疲劳、神经认知能力下降和睡眠障碍，也可能完全无症状。 注意：明确诊断需要基于多导睡眠呼吸监测和二氧化碳（CO2）监测（通过动脉、呼气末或经皮测量）的客观证据。

Idiopathic central alveolar hypoventilation is defined as the presence of decreased alveolar ventilation resulting in sleep related hypercapnia and hypoxemia in individuals with presumed normal mechanical properties of the lung and respiratory pump. Chronic hypoventilation during sleep exists without any readily identifiable impairments of respiration, such as pulmonary airway or parenchymal conditions, neurologic, neuromuscular or chest wall abnormalities, severe obesity, other sleep related breathing disorder, or use of respiratory depressant medications or substances. Diurnal as well as nocturnal hypoventilation is believed to be due primarily to blunted chemoresponsiveness to carbon dioxide (CO2) and oxygen (O2). Patients may complain of morning headaches, fatigue, neurocognitive decline and sleep disturbance, or may be entirely asymptomatic. Note: A definitive diagnosis requires objective evidence based on polysomnography with carbon dioxide (CO2) monitoring (by arterial, end-tidal or transcutaneous measures).

索引词 可用于检索该条目的同义词与别名

• 特发性中枢性肺泡低通气
• 特发性睡眠相关低通气
• 睡眠相关性非阻塞性肺泡低通气