肠道疾病引起的维生素B12缺乏性贫血

定义

许多肠道疾病也会导致维生素B12（钴胺素）缺乏。这些疾病包括严重的胰腺疾病和小肠疾病，如吸收不良、回肠疾病（包括结核性回肠炎、淋巴瘤、淀粉样样变、盆腔辐射的长期存活者）、广泛的小肠切除或旁路手术、肥胖症胃手术/重建（减肥手术）和克罗恩病。当空肠盲环存在时，盲环内细菌过度生长会争夺钴胺，导致钴胺素缺乏。虽然目前还不常见，但鱼绦虫的侵染，即阔节裂头绦虫，曾经是导致钴胺素缺乏的典型原因。

A number of intestinal disorders can also cause vitamin B12 (cobalamin) deficiency. These include severe pancreatic diseases and small bowel diseases such as malabsorption, ileal disease (including tuberculous ileitis, lymphoma, amyloid, long-term survivors of pelvic irradiation), extensive small bowel resection or bypass, gastric surgery/reconstruction for obesity (bariatric surgery) and Crohn's disease. When jejunal blind loops are present, bacterial overgrowth within the loops competes for cobalamin, leading to cobalamin deficiency. Although not as common currently, infestation with the fish tapeworm, Diphyllobothrium latum, was once a classic cause of cobalamin deficiency.

索引词 可用于检索该条目的同义词与别名

• 肠道疾病引起的维生素B12缺乏性贫血
• 继发于肠道疾病的维生素B12缺乏引起的获得性巨幼细胞性贫血