外阴鳞状细胞癌

定义

一种产生于外阴的浸润性鳞状细胞癌。风险因素包括人乳头瘤病毒和吸烟。癌前病变包括外阴上皮内瘤，伴鳞状细胞增生的硬化性苔藓样变，以及慢性肉芽肿性外阴病，如腹股沟肉芽肿。症状包括外阴瘙痒或刺激、分泌物、出血和疼痛。已确定的形态学变异有：角化型、非角化型、基底型、疣状型、疣状、角化棘皮瘤型，以及有肿瘤巨细胞的鳞状细胞癌。复发的危险因素包括晚期、肿瘤直径大于2.5厘米、多中心病灶、毛细血管样空间受累、伴2级或3级外阴上皮内瘤变，以及肿瘤累及的边缘切除。

An invasive squamous cell carcinoma arising from the vulva. Risk factors include the human papilloma virus and cigarette smoking. Precursor lesions include the vulvar intraepithelial neoplasia, lichen sclerosus with associated squamous cell hyperplasia, and chronic granulomatous vulvar disease such as granuloma inguinale. Symptoms include vulvar pruritus or irritation, discharge, bleeding, and pain. The following morphologic variants have been identified: keratinizing, non-keratinizing, basaloid, warty, verrucous, keratoacanthoma-like, and squamous cell carcinoma with tumour giant cells. Risk factors for recurrence include advanced stage, tumour diameter greater than 2.5 cm, multifocality, capillary-like space involvement, associated vulvar intraepithelial neoplasia grades 2 or 3, and margins of resection involved by tumour.

跨章引用 同一概念在其他章节另有编码

• 外阴疣状鳞状细胞癌2C31.0

索引词 可用于检索该条目的同义词与别名

• 外阴鳞状细胞癌
• 外阴鳞状细胞癌，HPV相关
• 外阴鳞状细胞癌，与HPV无关
• 外阴鳞状细胞癌，其他方面未特指