糙皮病

定义

糙皮病是一种潜在的威胁生命的疾病，由于烟酸缺乏和营养不良的个人，特别是酗酒者，并作为异烟肼治疗的并发症。诊断常被忽视或延误。糙皮病表现为腹泻、皮炎、痴呆，通常按此顺序出现。胃肠道症状总是先于皮肤受累，最初表现为晒伤样水疱性红斑，通常影响手、脸、颈、臂和脚背面。随着时间推移，皮肤增厚，出现鳞屑和色素沉着。

Pellagra is a potentially life-threatening disorder due to niacin deficiency and is observed in malnourished individuals, especially alcoholics, and as a complication of isoniazid therapy. The diagnosis is often overlooked or delayed. Pellagra manifests as diarrhoea, dermatitis, dementia, which usually appear in this order. Gastrointestinal tract symptoms always precede skin involvement, which presents initially with a sunburn-like blistering erythema, typically affecting the dorsal surfaces of the hands, face, neck, arms, and feet. With time the skin becomes thickened, scaly and pigmented.

索引词 可用于检索该条目的同义词与别名

• 糙皮病
• 类糙皮病综合征 [possible translation]
• 类糙皮病综合征
• 糙皮病多神经病