三倍体

定义

由一组额外的染色体引起的疾病，总共有69条染色体。三倍体可表现为母亲的白蛋白尿、水肿或高血压。如果是母系外遗传染色体，胎儿可能表现为小头畸形，胎盘增大并充满囊肿；而父系外遗传染色体则会导致严重的生长问题，头部增大，小胎盘无囊肿。非嵌合型三倍体具有高度致死性，活产很少。通过染色体核型分析观察一组额外染色体确诊。

A disease caused by one additional set of chromosomes, for a total of 69 chromosomes. Triploidy can present with albuminuria, oedema, or hypertension in the mother. The fetus may present with microcephaly and a placenta that is enlarged and filled with cysts in the case of extra maternally inherited chromosomes, while extra paternally inherited chromosomes cause severe growth problems, an enlarged head, and a small placenta that does not have cysts. Non-mosaic triploidy is highly lethal, and is rarely observed in live births. Confirmation is through observation of an additional set of chromosomes by karyotyping.

索引词 可用于检索该条目的同义词与别名

• 三倍体
• 三倍体
• 三倍体综合征