非酒精性脂肪性肝炎
Non-alcoholic steatohepatitis
- 上级条目
- DB92 非酒精性脂肪性肝病
- 层级
- 4 级
定义
非酒精性脂肪性肝炎 (NASH) 是非酒精性脂肪性肝病 (NAFLD)的一种组织学形式，其主要特征是肝细胞损伤的组织学证据（如气球样或麦洛利氏小体）和实质性小叶炎症。NASH通常与中央周围和窦周分布的纤维化有关（门脉纤维化模式也存在，尤其是在儿童）。NASH是NAFLD的临床进展形式，临床结果包括心血管事件、肝硬化或肝细胞癌。尽管已有报道了NASH的新生物标志物，但组织学仍然是诊断NASH的金标准。
Non-alcoholic steatohepatitis (NASH) is a histological form of Non-alcoholic fatty liver disease (NAFLD) in which the key features are histological evidence of hepatocyte injury (such as ballooning or Mallory hyaline) and substantial lobular inflammation. NASH is often associated with fibrosis in pericentral and perisinusoidal distribution (a portal fibrosis pattern also exists, particularly in children). NASH is the clinically progressive form of NAFLD with clinical outcomes including cardiovascular events, and cirrhosis or hepatocellular carcinoma. While novel biomarkers for NASH have been reported, histology remains the gold standard for diagnosis.
索引词 可用于检索该条目的同义词与别名
- 非酒精性脂肪性肝炎
- NASH[非酒精性脂肪性肝炎]
- 非酒精性脂肪性肝病
- 非酒精性脂肪性肝炎伴肝硬化
- NASH伴肝硬化
- 非酒精性脂肪性肝炎伴肝纤维化
- NASH不伴肝硬化
- 非酒精性脂肪性肝炎不伴肝硬化或肝纤维化
- NASH，未提及肝硬化
英文词条（9）
- Non-alcoholic steatohepatitis
- NASH - [non-alcoholic steatohepatitis]
- non-alcoholic steatohepatosis
- Non-alcoholic steatohepatitis with cirrhosis
- NASH with cirrhosis
- Non-alcoholic steatohepatitis with fibrosis
- NASH without cirrhosis
- Non-alcoholic steatohepatitis without cirrhosis or fibrosis
- NASH without mention of cirrhosis
后组配轴 Postcoordination
后组配是在主干编码之后追加的可选扩展轴（如侧别、具体解剖部位、严重程度），用于把「部位 + 侧别 + 病程」等细节一次表达完整。只有标注「必填」的轴在组合编码时必须给出，其余可留空。
- 临床表现hasManifestation可选
- 病程course可选