中毒源性神经病

定义

在考虑中毒性神经病的诊断时，应满足两个标准：（1）暴露可被证实，并与临床症状的出现有时间相关性。神经病症状通常与暴露同时发生，或在长达数月的可变潜伏期后发生(2） 必须有神经症状和异常的电诊断研究，因为许多中毒性神经病是亚临床的，主观症状可能发生，也可能不发生。脱离接触导致停止症状和缺陷的发展。大多数毒素以长度依赖的方式产生对称性轴突变性，开始于长而大口径神经纤维的远端，最终随持续暴露向近端扩散。除运动和/或感觉缺陷外，剧烈疼痛可能是一个特征。

In considering the diagnosis of toxic neuropathy, two criteria should be met: (1) Exposure can be verified and temporally related to the onset of clinical symptoms. Neuropathic symptoms usually occur concurrently with the exposure or following a variable latency of up to several months. (2) There must be neurological signs and abnormal electrodiagnostic studies, because many toxic neuropathies are subclinical, subjective symptoms may or may not occur. Removal from exposure results in cessation of progression of symptoms and the deficit. Most toxins produce symmetrical axonal degeneration in a length-dependent pattern, beginning in the distal segments of the long and large-calibre nerve fibres eventually spreading proximally with continued exposure. In addition to motor and/or sensory deficits, severe pain may be a characteristic feature.

跨章引用 同一概念在其他章节另有编码

• 酒精中毒性多神经病8D44.0

子条目 共 4 条

• 8D43.20药物性多神经病
• 8D43.21放射后多神经病
• 8D43.2Y其他特指的中毒源性神经病
• 8D43.2Z未特指的中毒源性神经病