经典型霍奇金淋巴瘤

定义

经典霍奇金淋巴瘤是一种B细胞淋巴瘤，其组织学特征是存在大的单核霍奇金细胞和多核Reed-Sternberg（HRS）细胞。 绝大多数情况下是一种单克隆B细胞淋巴增殖。其特点是年龄呈双峰分布（15-30岁和晚年），常与EB病毒感染有关。在不到5%的病例中，它是一种T淋巴细胞的单克隆增生。形态上，其特点是存在Reed-Sternberg细胞和单核霍奇金细胞。几乎所有病例的Reed-Sternberg细胞和单核霍奇金细胞都是CD30阳性，大多数病例的CD15阳性。

Classical Hodgkin lymphoma is a B-cell lymphoma characterised histologically by the presence of large mononuclear Hodgkin cells and multinucleated Reed-Sternberg (HRS) cells. A monoclonal B-cell lymphoproliferation in the vast majority of cases. It is characterised by a bimodal age distribution (15-30 years of life and late life) and is often associated with EBV infection. In less than 5% of cases it is a monoclonal proliferation of T-lymphocytes. Morphologically, it is characterised by the presence of Reed-Sternberg cells and mononuclear Hodgkin cells. The Reed-Sternberg and mononuclear Hodgkin cells are CD30 positive in nearly all cases and CD15 positive in the majority of cases.

包含词 该编码包含的临床情况，通常不作为独立编码

• 经典型霍奇金淋巴瘤，未特指型

子条目 共 5 条

• 2B30.10经典型霍奇金淋巴瘤，结节硬化型
• 2B30.11经典型霍奇金淋巴瘤，富于淋巴细胞型
• 2B30.12经典型霍奇金淋巴瘤，混合细胞型
• 2B30.13经典型霍奇金淋巴瘤，淋巴细胞消减型
• 2B30.1Z未特指的经典型霍奇金淋巴瘤