进行性眼外肌麻痹
Progressive external ophthalmoplegia
- 上级条目
- 9C82 眼外肌疾患
- 层级
- 4 级
定义
慢性眼肌麻痹的特点是眼肌和上睑提肌的进行性无力。这种情况主要表现在成年人身上。它可能是完全和永久孤立的，然而在少数情况下，它与骨骼肌病有关，引起异常疲劳，甚至是永久性肌无力。在这种情况下，这种病症仍被称为孤立性进行性外眼肌麻痹。大部分慢性眼肌麻痹表现为多系统体征：神经系统体征（听力损失、视网膜病变、小脑障碍、周围神经病变等）、内分泌（糖尿病、性腺功能减退、甲状旁腺功能减退等）、肾脏（肾衰竭、肾小管病变等）和心脏疾病（传导障碍、心肌病变等）。
Chronic ophthalmoplegia is characterised by progressive weakness of ocular muscles and levator muscle of the upper eyelid. The condition is mainly manifested in adults. It may be totally and permanently isolated, however in a minority of cases it is associated with skeletal myopathy, which causes abnormal fatigability and even permanent muscle weakness. In this case the affection is still termed isolated progressive external ophthalmoplegia. A large proportion of chronic ophthalmoplegias presents with multisystemic pattern of signs: neurological signs (hearing loss, retinopathy, cerebellar disorders, peripheral neuropathy, etc.), endocrine (diabetes, hypogonadism, hypoparathyroidism, etc.), kidney (kidney failure, tubulopathy, etc.), and heart disorders (conduction disorders, myocardiopathy, etc.).
索引词 可用于检索该条目的同义词与别名
- 进行性眼外肌麻痹
- 眼肌麻痹附加综合征
- 格雷费眼病
- PEO[进行性眼外肌麻痹]
- 格雷费氏病
- 进行性眼肌麻痹
- 甲状腺相关眼病
- 慢性进行性眼外肌麻痹
- CPEO[慢性进行性眼外肌麻痹]
- 慢性进行性眼肌麻痹
- 进行性眼外肌麻痹，常染色体显性遗传
- 进行性眼外肌麻痹，常染色体显性遗传
- 进行性眼外肌麻痹，常染色体显性遗传，1型
- PEOA1[进行性眼外肌麻痹，常染色体显性遗传，1型]
- 进行性眼外肌麻痹，常染色体显性遗传，2型
- 进行性眼外肌麻痹，常染色体显性遗传，3型
- PEOA3[进行性眼外肌麻痹，常染色体显性遗传，3型]
- 进行性眼外肌麻痹，常染色体显性遗传，4型
- 进行性眼外肌麻痹，常染色体显性遗传，5型
- PEOA5[进行性眼外肌麻痹，常染色体显性遗传，5型]
- 进行性眼外肌麻痹，常染色体隐性遗传
- Kearns-Sayre综合征
- KSS[Kearns-Sayre综合征]
- 眼-颅-躯体综合征
- 眼-颅-躯体营养不良
- OCS[眼-颅-躯体]综合征
- 眼-颅-躯体神经肌肉疾患
- 慢性眼外肌麻痹、视网膜色素变性、肌病和心肌病
- Kearns-Sayre线粒体细胞病
- 线粒体眼肌病
- 卡恩斯-塞尔线粒体细胞病
- 卡恩斯-塞尔综合征
- 眼-颅-躯体神经肌病
英文词条（27）
- Progressive external ophthalmoplegia
- Graefe disease
- PEO - [progressive external ophthalmoplegia]
- ophthalmoplegia plus syndrome
- Chronic progressive external ophthalmoplegia
- CPEO - [Chronic progressive external ophthalmoplegia]
- chronic progressive ophthalmoplegia
- Progressive external ophthalmoplegia, autosomal dominant
- PEOA - [Progressive external ophthalmoplegia, autosomal dominant]
- Progressive external ophthalmoplegia, autosomal dominant, type 1
- PEOA1 - [Progressive external ophthalmoplegia, autosomal dominant, type 1]
- Progressive external ophthalmoplegia, autosomal dominant, type 2
- Progressive external ophthalmoplegia, autosomal dominant, type 3
- PEOA3 - [progressive external ophthalmoplegia, autosomal dominant, type 3]
- Progressive external ophthalmoplegia, autosomal dominant, type 4
- Progressive external ophthalmoplegia, autosomal dominant, type 5
- PEOA5 - [progressive external ophthalmoplegia, autosomal dominant, type 5]
- Progressive external ophthalmoplegia, autosomal recessive
- Kearns-Sayre syndrome
- Chronic external ophthalmoplegia, pigmentary degeneration of retina, myopathy and cardiomyopathy
- KSS - [Kearns-Sayre syndrome]
- Kearns-Sayre mitochondrial cytopathy
- Mitochondrial ocular myopathy
- OCS - [oculocraniosomatic] syndrome
- oculocraniosomatic dystrophy
- oculocraniosomatic neuromuscular disorder
- oculocraniosomatic syndrome
后组配轴 Postcoordination
后组配是在主干编码之后追加的可选扩展轴（如侧别、具体解剖部位、严重程度），用于把「部位 + 侧别 + 病程」等细节一次表达完整。只有标注「必填」的轴在组合编码时必须给出，其余可留空。
- 侧别laterality可选