维生素A缺乏病伴角膜干燥症
Vitamin A deficiency with corneal xerosis
- 上级条目
- 5B55 维生素A缺乏
- 层级
- 5 级
定义
临床上，角膜出现典型的干燥，模糊，无光泽，干燥的外观，首先出现在下缘附近。许多儿童的角膜下鼻部有特征性的浅表点状病变，荧光染色明亮。在疾病早期，只有通过裂隙灯检查才能看到。随着病情加重，点状病变变得越来越多，并向上扩散到角膜中央，角膜基质水肿。角膜表面可形成类似Bitot斑的厚角质化斑块。这些通常在睑裂区最密集。经过治疗，这些角膜斑块会脱落，有时会留下表面糜烂，很快就会愈合。角膜干燥症在维生素A治疗后2-5天内有反应，1-2周后角膜恢复正常。
Clinically, the cornea develops classical xerosis, a hazy, lustreless, dry appearance, first apparent near the inferior limbus. Many children have characteristic superficial punctate lesions of the inferior-nasal aspects of their cornea that stain brightly with fluorescein. Early in the disease they are visible only through a slit-lamp examination. With more severe disease the punctate lesions become more numerous and spread upwards over the central cornea, and the corneal stroma becomes oedematous. Thick, keratinized plaques resembling Bitot's spot may form on the corneal surface. These are often densest in the interpalpebral zone. With treatment, these corneal plaques peel off, sometimes leaving superficial erosion which quickly heals. Corneal xerosis responds within 2-5 days to vitamin A therapy, the cornea regaining its normal appearance in 1-2 weeks.
索引词 可用于检索该条目的同义词与别名
- 维生素A缺乏病伴角膜干燥症
- 维生素A缺乏病伴角膜干燥症
英文词条（2）
- Vitamin A deficiency with corneal xerosis
- Vitamin A deficiency with cornea xerosis
后组配轴 Postcoordination
该条目未定义后组配轴，直接使用上面的编码即可。后组配是在主干编码之后追加侧别、具体解剖部位、严重程度、病因等细节的可选组合方式，不是必填项。