恶性高热或高烧

定义

恶性高热症是一种骨骼肌的药物遗传性疾病，表现为对强效挥发性麻醉气体如氟烷、七氟烷、地氟烷和去极化肌肉松弛剂琥珀胆碱的高代谢反应，在人类中很少出现对剧烈运动和高温等压力的反应。可能由Ryonadine受体1基因突变引起。

Malignant hyperthermia is a pharmacogenetic disorder of skeletal muscle that presents as a hypermetabolic response to potent volatile anaesthetic gases such as halothane, sevoflurane, desflurane and the depolarizing muscle relaxant succinylcholine, and rarely in humans, to stresses such as vigorous exercise and heat. May be caused by a mutation in the Ryonadine Receptor 1 gene.

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• 恶性高热或高烧