新生儿糖尿病

定义

新生儿糖尿病（NDM）是一种单基因糖尿病，发生在出生后6个月。这是一种罕见情况，每10万至50万活产婴儿中才有一例发生。患有NDM的婴儿不能产生足够的胰岛素，导致血糖升高。NDM可能被误认为是更常见的1型糖尿病，但1型糖尿病通常发生在出生后6个月。在大约一半的NDM患者中，这种情况是终身的，被称为永久性新生儿糖尿病（PNDM）。其余的NDM患者，病情短暂，在婴儿期消失，但在生命后期可能再次出现；这种类型的NDM称为暂时性新生儿糖尿病（TNDM）。

Neonatal diabetes mellitus (NDM) is a monogenic form of diabetes that occurs in the first 6 months of life. It is a rare condition occurring in only one in 100,000 to 500,000 live births. Infants with NDM do not produce enough insulin, leading to an increase in blood glucose. NDM can be mistaken for the much more common type 1 diabetes, but type 1 diabetes usually occurs later than the first 6 months of life. In about half of those with NDM, the condition is lifelong and is called permanent neonatal diabetes mellitus (PNDM). In the rest of those with NDM, the condition is transient and disappears during infancy but can reappear later in life; this type of NDM is called transient neonatal diabetes mellitus (TNDM).

子条目 共 3 条

• KB60.20新生儿暂时性糖尿病
• KB60.2Y其他特指的新生儿糖尿病
• KB60.2Z未特指的新生儿糖尿病