纤毛不动综合征

定义

呼吸道（下呼吸道和上呼吸道、鼻窦、咽鼓管、中耳）的纤毛功能缺陷，导致黏液纤毛传输改变，表现为反复上呼吸道和下呼吸道感染、慢性有痰咳嗽、慢性鼻炎鼻窦炎或持续性中耳炎。后天获得性疾病由呼吸道损伤引起，特别是与呼吸道感染如支气管炎或慢性阻塞性肺病有关。罕见的原发性疾病是作为常染色体隐性遗传疾病遗传的，在生命早期出现，通常进展为支气管扩张；由于精子活力或输卵管功能异常，它们可能分别与男性和女性的不育不孕症有关。

Defective function of the cilia lining the respiratory tract (lower and upper, sinuses, Eustachian tube, middle ear) resulting in altered mucociliary transport and manifesting as recurrent upper and lower respiratory infection, chronic productive cough, chronic rhinosinusitis or persistent otitis media. Acquired forms result from respiratory tract injury associated especially with respiratory infections such as bronchiolitis or chronic obstructive pulmonary disease. The rare primary forms are inherited as autosomal recessive disorders presenting early in life and typically progressing to bronchiectasis; they may be associated with infertility in men and women due to abnormal sperm motility or fallopian tube function respectively.

跨章引用 同一概念在其他章节另有编码

• 原发性纤毛运动障碍LA75.Y
• 综合征型纤毛运动障碍LA75.Y

索引词 可用于检索该条目的同义词与别名

• 纤毛不动综合征
• 纤毛运动障碍
• 不动纤毛综合征
• 继发性纤毛不动综合征
• 获得性纤毛运动障碍