弥漫性系膜硬化

定义

弥漫性肾小球硬化是一种组织学表现，其特征是基底膜弥漫性增厚，系膜面积大量增大，导致肾小球毛细血管束收缩和硬化。它可能见于因各种遗传异常导致的早发性激素耐药型肾病综合征的儿童，可作为孤立性肾病或多器官综合征的一部分。

Diffuse mesangial sclerosis is a histological appearance which is characterised by diffuse thickening of basement membrane and massive enlargement of mesangial areas leading to contraction and sclerosis of the glomerular capillary tuft. It may be seen in children with early onset steroid resistant nephrotic syndrome due to a variety of genetic abnormalities, either as an isolated renal disease or as part of a multi-organ syndrome.

索引词 可用于检索该条目的同义词与别名

• 弥漫性系膜硬化