疾病所致睡眠相关性低氧血症

定义

疾病所致睡眠相关性低氧血症的特征是睡眠期间 SpO2（通过脉搏血氧仪测量的血氧饱和度）持续下降（成人≤ 88% 或儿童≤ 90%，持续时间≥ 5 分钟）。这种情况可归因于内科或神经科疾病。其他与睡眠相关的呼吸障碍（如阻塞性睡眠呼吸暂停）不能更好地解释低氧血症的存在。虽然可能存在一定程度的阻塞性或中枢性呼吸暂停，但这些疾病不被认为是造成睡眠期间低氧血症的主要原因。有些睡眠相关低氧血症患者在清醒时也表现出低氧血症。如果已确定存在高碳酸血症，则应诊断为睡眠相关性通气不足，而不是睡眠相关性低氧血症。 注：确诊需要基于多导睡眠图监测动脉血氧饱和度（SaO2）的客观证据，前提是存在被判断为导致SaO2下降的疾病。

Sleep related hypoxemia due to a medical condition is characterised by sustained declines in SpO2 (oxygen saturation measured by pulse oximeter) (≤ 88% in adults or ≤ 90% in children for ≥ 5 minutes) during sleep. The condition is attributable to a medical or neurological disorder. The presence of hypoxemia is not better explained by another sleep related breathing disorder (e.g., obstructive sleep apnoea). Although some amount of obstructive or central apnoea may be present, these disorders are not thought to be primarily responsible for the hypoxemia during sleep. Some patients with sleep related hypoxemia also exhibit hypoxemia during wakefulness. If the presence of hypercapnia has been established, a diagnosis of sleep-related hypoventilation should be made, rather than sleep-related hypoxemia. Note: A definitive diagnosis requires objective evidence based on polysomnographic monitoring of oxygen saturation in arterial blood (SaO2) in the presence of a medical condition that is judged to be causing the declines in SaO2.

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• 疾病所致睡眠相关性低氧血症