原发部位滑膜肉瘤

定义

以染色体易位t（X；18）（p11；q11）为特征的恶性肿瘤。它可发生在任何年龄，但主要影响青壮年，更常见于男性。虽然任何部位都可受累，但绝大多数病例发生在四肢深部软组织，尤其是膝关节周围。在显微镜下，滑膜肉瘤可分为单相性（有梭形或上皮细胞成分）或双相性（有梭形细胞和上皮细胞成分）。滑膜肉瘤可复发或转移到肺、骨骼和淋巴结。

A malignant neoplasm characterised by the chromosomal translocation t(X;18)(p11;q11). It can occur at any age, but mainly affects young adults, more commonly males. Although any site can be affected, the vast majority of the cases arise in the deep soft tissues of extremities, especially around the knee. Microscopically, synovial sarcoma is classified as monophasic (with a spindle or epithelial cell component) or biphasic (with both spindle and epithelial cell components). Synovial sarcomas can recur or metastasize to the lungs, bones, and lymph nodes.

子条目 共 4 条

• 2B5A.0肢体软组织的滑膜肉瘤
• 2B5A.1呼吸道或胸内器官滑膜肉瘤
• 2B5A.Y其他特指原发部位的滑膜肉瘤
• 2B5A.Z未特指原发部位的滑膜肉瘤