钙化性动脉病

定义

钙化性动脉病（钙化防御）是一种威胁生命的血管病变，其特点是由于钙化、内膜纤维增生和皮下动脉血栓形成引起的疼痛性皮肤缺血和梗塞。它最常与终末期肾病或肾移植有关，特别是在长期糖尿病的情况下。受累皮肤通常位于臀部和大腿，在进展为全层梗死和深溃疡之前，出现斑点、灰色和失活。这些变化可能伴硬化的皮下斑块，表明有潜在的钙化性脂膜炎。这种情况可能是，但并不总是与甲状旁腺功能亢进或磷酸钙升高有关。

Calcific arteriolopathy (calciphylaxis) is a life-threatening vasculopathic disorder characterised by painful cutaneous ischaemia and infarction due to calcification, intimal fibroplasia, and thrombosis of subcutaneous arterioles. It is most commonly associated with end-stage kidney disease or renal transplantation, particularly in the context of longstanding diabetes mellitus. Affected skin, commonly on the hips and thighs, appears mottled, grey and devitalized before progressing to full thickness infarction and deep ulceration. These changes may be accompanied by indurated subcutaneous plaques indicating an underlying calcifying panniculitis. The condition may be but is not always associated with hyperparathyroidism or an elevated calcium-phosphate product.

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• 钙化防御

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• 钙化性动脉病
• 钙化性动脉病
• 钙化防御
• 钙性尿毒症性小动脉病
• 尿毒症相关性钙化防御
• 慢性肾脏病引起的钙性尿毒症性小动脉病
• 非尿毒症性钙化性小动脉病
• 非尿毒症相关性钙化防御
• 非尿毒症性钙化防御