原发性恶性雀斑样痣性黑色素瘤

定义

恶性黑色素瘤是恶性黑色素瘤的一种形式，当肿瘤细胞不再局限于表皮（原位放射状生长）而是侵入真皮（垂直生长）时，就会在恶性雀斑内发生。在侵入真皮之前，恶性痣可能一直以不规则色素斑的形式出现在暴露于阳光下的皮肤上多年。在侵袭的早期阶段，临床上可能无法与恶性痣鉴别，但随着肿瘤的进展，恶性痣内的局灶性增厚或结节将变得明显。

Lentigo maligna malignant melanoma is a form of melanoma which occurs within a lentigo maligna when neoplastic cells no longer remain confined to the epidermis (in situ radial growth) but invade the dermis (vertical growth). The lentigo maligna from which it arises may have been present as an irregularly pigmented macule on sun-exposed skin for many years before dermal invasion supervenes. Clinical differentiation from lentigo maligna may not be possible in the early stages of invasion but as the tumour progresses a focal thickening or nodule within the lentigo maligna will become apparent.

除外词 明确排除、需编到其他条目的情况

• 恶性小痣2E63.00

索引词 可用于检索该条目的同义词与别名

• 原发性恶性雀斑样痣性黑色素瘤