急性肾小管-间质肾炎

定义

以肾小管和肾间质急性炎症和损害为特征的疾病，通常伴有急性肾衰竭（急性肾损伤）。组织学显示肾间质急性炎症浸润，伴水肿和肾小管细胞坏死，并常可见嗜酸性粒细胞和浆细胞。通常由于对可识别过敏原的过敏性或免疫性反应。通常伴有急性肾衰竭，如果迅速停用过敏原，无论是否使用皮质类固醇，肾衰竭则可能可逆。可导致慢性肾小管间质性肾炎，特别是如果过敏原暴露并非短期的。可能与其他过敏反应的症状有关，如皮疹或发烧。

A disease characterised by acute inflammation of, and damage to, tubules and the interstitium of the kidney, usually accompanied by acute renal failure (acute kidney injury). Histology shows acute inflammatory infiltrate in the interstitium with oedema and tubular cell necrosis, and often prominent eosinophils and plasma cells. Usually due to an allergic or immunological reaction to an identifiable allergen. Usually accompanied by acute renal failure which may be reversible if the allergen is withdrawn expeditiously with or without corticosteroid administration. Can lead to chronic tubulointerstitial nephritis, particularly if the allergen exposure is not short term. May be associated with other signs of an allergic reaction such as rash or fever.

索引词 可用于检索该条目的同义词与别名

• 急性肾小管-间质肾炎
• AIN[急性间质性肾炎]
• ATIN[急性肾小管间质肾炎]
• 急性肾小管间质疾病
• ATIN[急性肾小管间质性肾炎]
• 急性肾小管间质性疾病
• 急性TIN[急性肾小管间质性肾炎] [possible translation]
• 急性TIN[急性肾小管间质性肾炎]
• 药物、生物制剂或毒素引起的急性肾小管间质性肾炎
• 感染性病原体引起的急性肾小管间质性肾炎
• 急性感染性小管间质性肾炎
• 急性感染性间质性肾炎
• 感染性急性小管间质性肾炎
• 与免疫疾患有关的急性肾小管间质性肾炎
• 急性尿酸性肾病
• 急性高尿酸血症肾病