Waterhouse-Friderichsen综合征

定义

一种由于严重感染导致肾上腺出血（多为双侧，有时为单侧）而引起的，以肾上腺功能不全为特征的综合征。通常由脑膜炎球菌感染（脑膜炎奈瑟菌）引起。然而，它也可能是由肺炎链球菌或流感嗜血杆菌等其他细菌感染引起的，甚至是由一些严重的病毒感染引起。 该综合征可表现为发热、寒战、呕吐、肌痛或皮疹，并逐渐发展为弥散性血管内凝血。潜在感染是通过直接接触或飞沫传播。

A syndrome characterised by adrenal insufficiency due to bleeding into the adrenal glands (mostly bilateral but sometimes also unilateral) due to the severe infection, commonly caused by an infection with meningococcus (Neisseria meningitidis). However, it can also be caused by infections with other bacteria such as Streptococcus pneumoniae or Haemophilus influenzae or even due to some severe viral infections. This syndrome may present with fever, chills, vomiting, myalgia, or rash, with progression to disseminated intravascular coagulation. Transmission of the underlying infections is by direct contact or droplet transmission.

包含词 该编码包含的临床情况，通常不作为独立编码

• 脑膜炎球菌性出血性肾上腺炎

索引词 可用于检索该条目的同义词与别名

• Waterhouse-Friderichsen综合征
• 脑膜炎球菌感染所致华-弗综合征
• Waterhouse-Friderichsen病
• 脑膜炎球菌性肾上腺综合征
• 出血性脑膜炎球菌性肾上腺炎
• 急性肾上腺功能不全合并脑膜炎球菌败血症（弃用）
• 肾上腺出血综合征
• 脑膜炎球菌性出血性肾上腺炎
• 沃-弗综合征
• 华-弗综合征