固定性药疹

定义

固定性药疹是指全身暴露于药物后，皮肤上出现一个或多个环形或椭圆形炎性红斑。这些斑块可发展成大疱。炎性斑块通常随炎症后色素沉着而消退，但通常在同一部位复发，通常在每次再次接触药物后，累及部位逐渐增多。在极端情况下（全身大疱性固定性药疹），临床表现可能与中毒性表皮坏死松解相似。大量药物被认为是诱因。

The term fixed drug eruption describes the development of one or more annular or oval inflamed erythematous patches on the skin as a result of systemic exposure to a drug. The patches may develop into bullae. The inflamed patches normally resolve with post-inflammatory hyperpigmentation but typically recur at the same site(s), often with progressively more involved sites, following each reexposure to the drug. In extreme cases (generalised bullous fixed drug eruption) the clinical picture may mimic toxic epidermal necrolysis. A large number of drugs have been implicated as triggers.

索引词 可用于检索该条目的同义词与别名

• 固定性药疹
• 局限型固定性药疹
• 全身性大疱性固定性药疹