Mikulicz 病
Mikulicz disease
- 层级
- 4 级
定义
米库利兹病是1892年约翰·冯·米库利兹首次报告的一种疾病，其特征是泪腺、下颌下腺和腮腺对称肿胀，这些腺体被单核细胞大量浸润。血清自身抗体，如抗Ro/SS-A，通常为阴性，血清IgG4浓度可能升高。与Sjögren病不同，IgG4-mikuliz病以淋巴滤泡形成为特征，但淋巴细胞对唾液腺导管的浸润程度较低，使其结构保持完整。
Mikulicz disease is a disorder first reported by Johann von Mikulicz in 1892 and characterised by symmetrical swelling of the lachrymal, submandibular, and parotid glands, with massive infiltration of these glands by mononuclear cells. Serum autoantibodies, such as anti-Ro/SS-A, are usually negative and serum IgG4 concentration may be increased. Unlike Sjögren disease, IgG4-Mikulicz disease is characterised by the formation of lymphoid follicles, but shows lower levels of lymphocytic infiltration into salivary ducts, such that their structure remains intact.
索引词 可用于检索该条目的同义词与别名
- Mikulicz 病
- 米库利兹病
- 米库利奇病
英文词条（1）
- Mikulicz disease
后组配轴 Postcoordination
该条目未定义后组配轴，直接使用上面的编码即可。后组配是在主干编码之后追加侧别、具体解剖部位、严重程度、病因等细节的可选组合方式，不是必填项。