药物或物质所致中枢性睡眠呼吸暂停

定义

药物所致中枢性睡眠呼吸暂停的特征是一种反复发作的、主要是中枢性睡眠呼吸暂停或呼吸减弱（每小时超过五次）的模式，可归因于药物或物质，最常见的是长效阿片类药物（如美沙酮、长效吗啡或羟考酮、芬太尼贴剂）。这种干扰严重到足以引起白天嗜睡、睡眠紊乱、醒来时呼吸困难或打鼾等症状。可能出现阻塞性呼吸暂停和通气不足，但主要表现是中枢性睡眠呼吸暂停。 注：明确诊断需要多导睡眠呼吸监测的客观证据，并结合药物使用情况来判断是否导致这些症状。

Central sleep apnoea due to a medication is characterised by a pattern of recurring, predominantly central sleep apnoea or hypopnoea (more than five per hour) that is attributable to a medication or substance, most commonly long-acting opioids (e.g. methadone, long-acting morphine or oxycodone, fentanyl patches). The disturbance is sufficiently severe to cause symptoms such as daytime sleepiness, disturbed sleep, awakening with dyspnoea, or snoring. Obstructive apnoeas and hypoventilation may be present, but central sleep apnoea is the predominant finding. Note: A definitive diagnosis requires objective evidence based on polysomnography in the context of medication or substance use that is judged to be causing the symptoms.

索引词 可用于检索该条目的同义词与别名

• 药物或物质所致中枢性睡眠呼吸暂停
• 物质（包括药物）引起的中枢性睡眠呼吸暂停