口面部肉芽肿病
Orofacial granulomatosis
- 层级
- 5 级
定义
口腔颌面部肉芽肿性疾病（OFG）是一种罕见临床病理实体，其特征为持续和/或复发性淋巴水肿、嘴唇和口腔粘膜裂开（后者导致“鹅卵石”外观）、口腔溃疡和活检非干酪化肉芽肿。OFG可能是克罗恩病的早期表现，有时在肠道疾病前数月或数年出现。有些病例与牙齿感染、结节病、食物过敏或接触性过敏有关。肉芽肿性唇炎是一种局限于嘴唇的OFG。极少数情况下，OFG可能与舌裂和面神经麻痹（梅-罗综合征）有关。
Orofacial granulomatosis (OFG) is an uncommon clinicopathological entity characterised by persistent and/or recurrent lymphoedema and fissuring of the lips and oral mucosa (the latter resulting in a "cobblestone" appearance), oral ulceration and the presence on biopsy of non-caseating granulomas. OFG may be an early manifestation of Crohn disease, sometimes presenting months or years before bowel disease. Some cases are associated with dental infections, sarcoidosis, food allergy or contact allergy. Granulomatous cheilitis is a form of OFG confined to the lips. Rarely, OFG may be associated with fissured tongue and facial palsy (Melkersson-Rosenthal syndrome).
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- 口面部肉芽肿病
- 口腔颌面部肉芽肿性疾病
英文词条（1）
- Orofacial granulomatosis
后组配轴 Postcoordination
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